Computational and Mathematical Methods in Medicine
Volume 2013 (2013), Article ID 767296, 8 pages
http://dx.doi.org/10.1155/2013/767296
Research Article

Improved Reconstruction Quality of Bioluminescent Images by Combining SP3 Equations and Bregman Iteration Method

Qiang Wu, Jinchao Feng, Kebin Jia, and Xiangyu Wang

College of Electronic Information and Control Engineering, Beijing University of Technology, Beijing 100124, China

Received 13 September 2012; Accepted 24 December 2012

Academic Editor: Jimin Liang

Copyright © 2013 Qiang Wu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Bioluminescence tomography (BLT) has a great potential to provide a powerful tool for tumor detection, monitoring tumor therapy progress, and drug development; developing new reconstruction algorithms will advance the technique to practical applications. In the paper, we propose a BLT reconstruction algorithm by combining SP3 equations and Bregman iteration method to improve the quality of reconstructed sources. The numerical results for homogeneous and heterogeneous phantoms are very encouraging and give significant improvement over the algorithms without the use of SP3 equations and Bregman iteration method.